Thursday, April 16, 2020

Community Spread of Covid -19: Not Yet


By Dr. Lakshman Abeyagunawardene
MBBS; MPH; MD (Community Medicine)
Consultant Community Physician

It is quite possible that some sections of the general public may be confused by the constant reference to “semi technical” terms when discussing the Covid-19 outbreak. To put the record straight, let me at the outset explain that these are really epidemiological (or technical) terms. I refer here to pandemics, epidemics and endemics. Though it sounds simple, “community spread” is also a technical term in that it means that the victim picked up the disease from some unknown infected person with whom the person had come into contact (as opposed to those who have had some form of contact with a foreigner, tourist guide, chef etc.)

The Centers for Disease Control (CDC) refers to such terms as pandemic, epidemic and endemic with the technical aspect in mind. The media in Sri Lanka use the term pandemic more broadly to describe the present outbreak of Covid-19 .  The local media cannot be found fault with because the disease has spread over several countries or continents and appears to be presently out of control. It is also affecting a high proportion of the population.  An epidemic in its true sense, refers to an increase, often sudden, in the number of cases of a disease above what is normally expected in that population in that area (eg. Outbreaks of smallpox in Sri Lanka in the past). For the sake of completeness , an endemic refers to the constant presence and/or usual prevalence of a disease or infectious agent in a population at the baseline level within a geographic area (cholera was endemic in some areas in Sri Lanka some time ago)

This explanation is considered important because terms like these direct the public health response to better control and prevent the present outbreak. Moreover, the WHO and the Ministry of Health also use these terms quite liberally.

An Epidemiologist’s Dream

Although I have specialised in a different branch of Public health, I had an abiding interest in the subject of Epidemiology even when I was doing my MPH in Berkeley, California, 46 years ago. This has continued up to date and I always look at epidemics and pandemics in a special way. The present outbreak of Covid-19 is not an exception and in my opinion, has proved to be an Epidemiologist's dream.

The very first case of the deadly disease in Sri Lanka was confirmed on 27 January when a 44-year-old Chinese woman from Hubei Province in China was admitted to the National Institute of Infectious Diseases (IDH). She had arrived as a tourist with a group of travellers and had been screened at the Bandaranaike International Airport after having a high fever. She had fully recovered and was released from hospital on 19 February.

Like other countries, Sri Lanka too has gone through troubled times due to the pandemic. However, although we have 233 confirmed cases as of 15th April, we have not yet gone into the stage when community spread of the disease has occurred. All cases confirmed so far, have had some contact with the outside world (employees returning from countries like Italy and South Korea, foreign tourists, tourist guides or their relatives). For instance, the uncharacteristic spike of 21 cases in one day, includes many members of one family. Similarly the sharp rise of confirmed cases seen on April 14th when only those from quarantine centres were PCR tested, the results of which ruled out free community spread. In other words, Community spread has not yet begun. Therefore, it is not difficult to contain the outbreak at this stage.

I must confess here that I have only a passing interest in Sri Lankan politics. Like most other citizens, when elections come round, I dutifully exercise my voting right. Depending on the prevailing situation, both leading political parties in turn have succeeded in securing my vote. Whatever others may say, I feel that we are in the fortunate position in that we have a militarily trained President in His Excellency Gotabaya Rajapaksa and a Defence Secretary Major General Kamal Gunaratne to guide our destinies at this time. The Director General of Health Services Dr. Anil Jasinghe and the present Army Commander Shavendra Silva who heads the Media Task Force, have an abundance of intelligence and a good grasp of the problem. The communication support provided by DIG Ajith Rohana who is a lawyer, is also commendable. The professional associations, medical consultants, community physicians (especially of the Health Promotion Bureau) and even trade unions like the GMOA have chipped in by providing much needed technical advice to the government. Particular mention should be made of Dr. Paba Palihawadana and Dr. Sudath Samaraweera who have been in the forefront offering technical support from Day 1.

Another important supportive group has been the Intelligence Unit of the Sri Lanka Army. I believe Sri Lanka is the only country in the world that has utilized the services of Army Intelligence for epidemiological investigations. They have done a tremendous job in successfully carrying out contact tracing.

I wonder whether we have already begun to see the light at the end of the tunnel. Other than the districts (Colombo, Gampaha, Kalutara, Puttalam, Kandy and Jaffna) which have been classified as high-risk areas, in the other districts, the curfew is being relaxed gradually. Even in the so called high-risk areas, moves are afoot to bring in more relief to the masses. These are all good signs. The government is anxious to see that SL's citizens are given lesser burdens and more freedom, but they simply can't do it all at once due to the enormity of the outbreak.

On the part of the general public, I wish to make this concluding fervent appeal to continue with behaviours such as social distancing, proper hand washing, wearing face masks as advised by the Health Ministry and avoiding congregation in public places. It is only then that we would be able to close this unfortunate chapter.

If Wuhan could do it, we certainly can!

76 comments:

  1. Lucky
    Thank you for that fine summary of the progress of the disease in SL and explaining some of the terms used to confuse the layman like myself. My knowledge of public health evaporated into thin air as I left the precincts of our Temple of Wisdom on Kynsey Road.
    In the UK the tunnel seems longer and the light at the end still some distance away.
    My understanding is that testing, contact tracing and isolation are the back bone of the management of any epidemic. This was slow to take place in the UK complicated by the many who travel into the country from all parts of the world. We are a paying a heavy price for this delay.
    I wonder what your views are of the WHO. They certainly got it wrong at the beginning of this epidemic. I am not impressed by the way this difficult situation is managed by them. I do appreciate their other work in the 3rd world on malaria etc. I remember the kerfuffle over 50 years ago when the WHO advised the Dept of Health in SL to withdraw the spraying units as we had no malaria when all hell broke loose and we were confronted with yet another epidemic.
    Speaking of Public Health I wish to pay tribute to Prof OE Abhayatane. As Pramilla and Sanath Lama pointed out at our Zoom the basics he taught still ring true. Public Health lectures by him were light entertainment in memorable English prose laced with rhyming poetry. His kind avuncular manner endeared him to his students. A true gentleman in every sense of the word. Rest in Peace

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  2. Lucky, a most scholarly article. Thank you for clarifying definitions. I am no longer surprised when I hear discussions and often heated arguments caused by a simple failure to define terms that are being used. In the field of Science, many lay people (and even men of Science) fail to understand that common English words may have a different meaning in science. You have given some good epidemiological definitions but even in General Medicine, lay people use the word Dementia for example, or even Immunity without appreciating that these are define medical words.

    As we discussed at the Zoom meeting, we are so impressed by the professional, logical and efficient way that Sri Lanka dealt with this crisis. The key appears to be strong leadership backed by good medial advice. I do hope that SrI Lanka will not only overcome this but go on to deal with other important issues in this manner. The worry we have hear is the influence of corruption and nepotism.

    Like Nihal,I too would appreciate your views on the WHO. I think it is despicable of Trump to withdraw support at this crucial moment but then we are used to "Trumpism"!

    Thanks again and I hope this is just the beginning of more posts form you on the Blog.

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  3. This is a common comment on the two comments made by ND and Speedy.

    Trump should not have used this crucial moment to stop US funding. There have been threats in the past by former US Presidents to do so at disagreements over various issues, but personally, I never thought that Trump would carry out his threat. Anyway, now that he has acted, it is up to the WHO DG Dr Tedros to manage without crucial funding. As ND has pointed out, the WHO had erred in the past and also gave the impression that they were partial towards China knowing very well that the US would react. What I feel is that the Ethiopean Microbiologist will learn fast not to mix politics with UN affairs.

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  4. Lucky, I really enjoyed reading your article written by an expert in the field. I think you should send it to the e-edition of the Island paper but as hard copies are not currently available , it will only be read by a lesser number of people.
    I heard some disturbing news today. A person who was released after being in quarantine for two weeks,had fallen ill after going home and then tested positive for Covid 19. I am not sure whether the test was done at the time of release. Learning from this patient's experience, I wonder whether the people after been released after two weeks of quarantine, should be confined to their homes for another extended period of one or two weeks.I am also of the opinion that all people should be tested with the PCR test before and after the period of quarantine is over.

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  5. I was a bit concerned that with the curfew on, circulation of all newspapers is limited or hardly any.

    I too heard that story about reinfection. On TV I heard today that some 138 ex patients in South Korea had got a second attack of the virus. If that happens in SL, I wonder whether the authorities are equipped to handle such a situation. I also heard that at least some people are now tested (PCR)before and after quarantine. The Director MRI says that over 100 PCR tests are being done now now. I also watched on TV, Shavendra Silva saying that even those completing the quarantine period in camps have to be at home for two more weeks (under supervision).

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  6. Lucky,There is doubt about the level of immunity and how long it would,last.Secondly,there is a possibility that reactivation of remaining viral particles multiplying as a result of a weak immune response to the primary infection.Getting a viral infection seems to impart complete immunity against vaccination with manufactured anti viral agents.I am no virologist.

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  7. Sumathi and Lucky
    Re Reinfection.
    I am no virologist either but I read something on similar lines.Director of Korean Centre for Disease Control(KCDC) had stated 4 days ago that for now they are still uncertain whether it is reactivation or fresh exposure.

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  8. Congratulations Lucky on your erudite and comprehensive article.It certainly would explain to lay people many concepts which are difficult to understand.
    I definitely agree that it has been well managed in SriLanka; great credit to our technocrats and administrators.Begs the question whether we need politicians at all or at least in such excessive numbers.Look forward to more from you.

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  9. Nihal
    I too enjoyed Prof Abhayaratnes's lectures.I remember him telling us about a Third MB Public Health Viva.He asked the candidate what the "Triple Vaccine" Contained.The student took his time and very slowly replied,pausing after each word Bacillus-Calmette and Guerin.
    I will never forget how the Dean summoned all the males in our batch to investigate "The Castle Street Incident".He threatened to use the Electron Microscope to identify the culprits.

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    1. Bora
      I remember well that late morning on a hot day when we were summoned to gather in a large room in the administrative block. There may have been around 80 of us, all men. The ceiling fans turned slowly to churn out our latent fears. A crime had been committed and the Police and the public had great faith in Prof OER to deal with the issues equitably. I remember the regal frame of Prof OER seated on the throne. He was the judge, jury and the prosecution. It was an ordeal and a terrifying experience for us all. He dismantled ruthlessly some of the ridiculous things that were said in the heat of the moment and did his best to be abrasive. We were reaching the end of the ‘cross examination’ when it had been established beyond any reasonable doubt the lorry had entered the Castle Street Girl’s School. The question was asked “ Who entered the premises of the school”. A few reluctantly raised their hands knowing well the punishment for the ultimate crime if proven was the ‘death penalty’. Then he went on to ask “who are the students who were in the lorry”. More hands were raised. A guy seated in the front row, a well-known maverick, was sweating and mopping his brow. He had raised his hands like a few others that he was in the lorry but did not go into the premises. The Prof most astutely noted this and questioned him further. He stammered and got it out of his chest that only one half of the lorry entered the premises and he was in the other half. The Prof rolled his eyes up and continued on. We all realised the humour at the time but were in no mood to laugh our lives being at stake. As a group we cannot thank Prof OER for being the judge, jury and the prosecution. We all got off lightly for a very serious crime – changed from homicide to culpable homicide not amounting to murder!! He had to show that justice was seen to be done. Amazingly, no person was singled out. The punishment was collective and as many of us feel even now, was appropriate. What we got was a suspended sentence having to pay the court cost and for the counsel!! Amazingly no entry was made on our CV’s.
      Beneath that austere and stern exterior lay a kind and humane soul. There are occasions when it has crossed my mind we perhaps owe our careers to this great man. If this happened in the 21st Century we all may have been sacked. Reading the Blogs from other batches a common thread I notice is that they all deify the good Professor. I would say it again” May his Soul Rest in Peace.

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    2. ND ,You have given an excellent description of the event.Pof OER A had the wisdom of Solomon.He was also a father,compassionate and well aware of foibles of generations of medical students.A truly great man.

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    3. Kumar and my other learned colleagues
      I do hope Rohini Abhayaratne is able to see what we think of her father. He was indeed a father figure to us all as you have rightly said, Kumar.

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  10. Lucky,
    The ‘containment ‘ of Covid in SL has been admirable and I hope it stays that way.
    Thank you for giving us a picture of those who have contributed to making this possible.
    The numbers of confirmed cases in a population of 20 million people in SL is encouragingly and amazingly low.
    This would of course depend on the number and criteria for testing .
    The true numbers of asymptomatic infected persons cannot be known until random testing is done in communities as is now being done in New Zealand and in some states in Australia eg Melbourne . I wonder how much testing capability SL has had.
    I cannot imagine the resourses needed to random test populations in SL.

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    1. I am going by TV news. Today, I heard that the Health Ministry is capable of doing about 1500 PCR tests per day. Today, they were expecting the results of yesterday's 220 odd tests. GMOA is pressing to step up this figure. Whole of yesterday, the number of positives was zero.

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    2. This is fantastic - thank you Lucky

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  11. I remember Prof.OER A asking why a pit latrine is 40 feet deep. A bright spark answered "that is to prevent round worms crawling out"!

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    1. Sanath
      Latrines were an important issue in public health and the good Prof revelled in its descriptions and construction. I recall the squatting plates which he advocated with the elevated area to place the feet with the heels together and the toes far apart. On my travels I used one in which the Public Health Inspector had got the mould wrong and had the toes together and heels far apart. Fortunately I was young enough then to continue my ablutions in a difficult yoga position.

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  12. Rohini, at present we have 116 PCR machines in the country and each machine could test about 20 samples per day. There are some logistic issues like insufficient naso-pharyngeal swabs and viral transport media. I am personally aware that at the MRI, doctors and MLTs are burning the midnight oil attending to these tasks. In my humble opinion, in those who are under state quarantine, at least a minimum of two tests should be carried out , two weeks apart. I am not aware whether the testing has widened to include those under voluntary home quarantine. That should be the logical next step.

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  13. Yes of course testing should include those in voluntary home quarantine.
    In this crisis SL has acted quickly and done admirably. My best wishes to all those involved and working hard to keep the people safe. Thank you Sanath.

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  15. To all my learned friends
    In Radiology we never need microbiology and pharmacology. As a result those important subjects underwent disuse atrophy. So my knowledge of virology is a meagre remnant from what I learnt from the monotonous drone of Prof Terence Chapman and also Fairbrother’s Text Book of Bacteriology.
    Viruses have the propensity to mutate with a change in their antigenicity. This would be a nightmare to develop a vaccine and also to do the testing. If there is heightening of its virulence it would indeed be hard to contain and manage. Of course I’m thinking of the worst case scenario. Hopefully everything will be fine with time. If not it will be Armageddon and the end of life as we know it, just like the disappearance of dinosaurs with a meteor strike.
    The Spanish flu of 1918 caused tremendous loss of life. Some estimates go upto 100 million deaths with a quarter of the population of this planet being affected.
    Let us look at the bright side of life. There is a glimmer of hope at least in some countries they are winning the war. As Asoka Wijeyakoon rightly pointed out the other day. A glass of wine a day keeps the doctor away.

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  16. You are quite right Nihal - It is indeed a nightmare to think that with each mutation a new vaccine will have to be developed just like it has been with the Flu vaccine and also the possibility that it could become a seasonal menace - Besides, the mutations could be so fast and unpredictable it could be Impossible to keep in step.
    Here start all the conspiracy theories - deadly serious !

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    1. P.S. I prefer to believe human beings are not that evil !

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  17. Nihal!An apple a day keeps the doctor away.As Rohini has highlighted,blame culture is a fairly common entity.Some may say that evil doers have outraged the Creator.Others may say that it is Godesses Paththini who has sent this virus to this world.I am sure some of the villagers in Sri Lanka might have already started Poojas.Monks have started chanting the Rathana Sutra.During my childhood I have seen families offering food to "Kiriammas(females who have given birth in the past),whenever a family member had an attack of chickenpox.I do not think that was a practiced by the town folks.I wondered the mass deaths are a way of controlling the rapid increase of the population.Charles Darwin's theory of the survival of the fittest,explains well.
    .

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  18. Thanks Lucky for educating all of us in Public health , and statistics. I remember our days when we all thought Public health was a joke and Dr Basanayake teaching us statistics and here we are now at a time of Catastrophy looking for Public health measures to contain the Virus and statistical models to predict the future and the death rate. In the past many of us paid little respect for the MPH but after this our eyes will be open I wish we had a second chance

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  19. Rajan, I think it was Earle Fonseka who taught us statistics.

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    1. “There are three kinds of lies;lies,damned lies and statistics “
      Attributed to Benjamin Disraeli and popularised by Mark Twain.
      We were not taught that at Medical School.!!!

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    2. Many use statistics as a drunken man uses lamp posts - for support rather than for illumination - Andrew Lang

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  20. I spoke to an immunologist working at the MRI which is one of the places where PCR testing is done. He told me that tests are done only at the time of release from quarantine and not at the time of entry.

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  21. You are correct,Sanath,Dr Weerasinghe taught us nutritional aspect of food.I,certainly could not make head nor tail of Medical statistics.Lama was the only one to obtain a Distinction on Public health at the 3rd MB exam.I am sure lot of our friends have already forgotten about it.
    As far as DPH & MPH Postgraduate degrees are concerned,they were looked down as Second class Specialities.In UK ,Diplomas are meant for export to the third World.

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    1. I thought Pram also got a Distinction?

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    2. I knew nothing of statistics and still don't . All my PH knowledge was bought for Rs.5/- from Marker and sold it back to Marker for Rs 2.50. That was a good bargain for a pass.

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    3. Nihal
      Tell me,did you purchase a set of PH notes from the" Billiard Marker".What a pity I was not aware that the notes were available from BM.

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    4. Bora
      The PH notes were cyclostyled and showed it’s age but were good. There was a huge demand for those. They even included all Prof OeR’s jokes inserted in the right place.

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  22. Nihal
    A friend of mine who was six years junior to me told me that during his time Billiard Marker had a lucrative business selling sets of notes on Medicine,Surgery etc and getting good results.
    Dr David Chanmugam during a ward class asked a student for the DD of PUO.He was disappointed with the answer and asked him what book he was reading.The student replied Medicine by Davidson(or something similar), he was advised to change the book.
    Dr D.C then asked the same question from another boy and was very pleased with the response, so much so that Dr D.C asked the student what book do you read,it can't be Davidson?."No sir,my book is "MEDICINE by Prof BILLY MARKER"

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    1. I can well imagine Marker diversifying his business to include other subjects. This was a money spinner for him. The Billy Marker story has the hallmarks of one of those Boralessa specials. Fact or fiction it is well appreciated.

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  23. Nihal,
    Thank you for your “ball by ball “ account of the proceedings followings the Castle St. incident. Well written and amusing in retrospect, but obviously was far from amusing then !
    Prof O.E.R.A was indeed a fascinating and lovable character whose humanity and wisdom saved the future of a batch of over-exuberant medics from their own folly !
    He will be admired and loved by many - May he have eternal Peace.


    written and

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    1. Rohini
      Thank you for the comment. Youthful exuberance and alcohol are a lethal combination. Writing about it makes my hair stand on end even after more than half a century.

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  24. Talking of Prof OER I did not pass Public health ( wish I had known of Markers notes) and those of us who did not make it had a session with the dear Prof. Among those who also failed was Walter Jayasinghe who had returned from the US with a MPH. He was asked why he had failed and Walter responded " sir you know as I of the toilets in the US and those in Ceylon the 4FtX4ft with 2x2 hole in the ground with a roof of tin that is hot on a sunny day and noisy on a rainy day and before Walter could finish The good old professor asked him to sit down. I wander how Walter would have finished.

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  25. Nihal
    One needs a lot of imagination to make up a story like this,beyond my capabilities.One of Mahen's former neurology SHO's related this story to me,could be fact or fiction,I must check this out when I next speak to him.I have heard that some writers do not let the truth get in the way of a good story ,not me j

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  26. Rajan
    I was in the Blom 1966/67 and shared a room with my good friend Kumar.One day I heard Walter complaining that when he was in the USA he had to study the complications of overnutrition now he had to learn about the effects of malnutrition,

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  27. Nihal
    In my previous comment to you,the "some writers" I referred to were the writers to magazines etc not to our bloggers.

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    1. Bora
      No harm at all being economical with the truth to bring on a laugh. It is for a good cause. With a sound mix of fact and fiction you've done it successfully from the time I can remember. Specially at this time when good news is in such short supply your input is most welcome.

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  28. Our death rate due to Covid 19 so far is about 3 per million which compares very well with other countries.. In the us is 80, South Korea 4 and in Taiwan <1.

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  29. In 1971 the MRCP Part 1 was conducted in Ceylon, for the first time. There were about 60 of us who were in the examination hall, in the premises of the Colombo Medical Faculty.At 2.30 pm, a person from the British Council, dressed in a lounge suit came and looked at his wrist watch and opened a bundle. Each paper consisted of 60 MCQs of the True/False type, five responses in each and duration was for three hours. After about an hour, a candidate also dressed in a lounge suit, left the hall. I have not seen him since then! I was the next person to leave after another 30 minutes or so. Other candidates stared at me when I left.
    The next morning, I recollected all 300 questions and I gave it to our office secretary, who happened to be Dr. Douglas Wickramasinghe's sister for typing. In one question she had mis-spelt soya flour as Soysa flour! Thereafter there was a very big demand for my paper because there was no MCQ question banks at that time.Later the Marker got hold of my paper, cyclo-styled it (as there were no photocopiers then) and minted money! The pass rate was relatively high,Russell Paul and myself passed.

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  30. To all my learned friends
    Pramilla Senanayake most kindly sent me an article written by Dr Lucien Jayasuriya. I cannot quite place him but I’ve been away from SL for nearly 50 years. He has mentioned he was president of the SLMA in 1995. Certainly not a mere mortal like myself!! Without being patronising I must say how well it is written. He and his wife travelled from London to Sri Lanka in March and was quarantined with several others in a Military Camp near Vavuniya. They were all treated with kindness, care and compassion. The food was good. The toilets were clean and hygienic. Everything worked with Military precision from the time they arrived on the facility until their departure. Even the occupant’s medical needs were well catered for. The account makes me so very proud to be Sri Lankan. I wish the other countries learn from us how quarantine should be provided in the 21st Century.

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    1. Lucian and Nimala are now resident in Sri Lanka. They visit their two sons in UK almost every year. This happened while returning from UK on their last trip. Lucian graduated in 1962 and has been a Medical Administrator. He was Director General of Teaching Hospitals when the Ministry was broken down to two and later was Additional Secretary, Health. Sanath Lama too knows him well.

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  31. I have known Lucian for a very long time. I spoke to him after both of them had returned from quarantine. He was full of praise for everyone. However, he had been rather anxious at the onset because he has cardiac problems and is on medication. He was sent to a facility in the Wanni located between Vavuniya and Mannar. Perhaps he should have been sent to a more accessible place, in case he developed cardiac problems.
    Nihal, I sent you a Ada Derana video where students who had been released from quarantine are interviewed. Some parents including a Britisher who is the General Manager of Shangri La Hotel were interviewed as well. All of them heaped praise on our armed forces. Please post your comments after watching it. Right now I feel proud to be a Sri Lankan, domiciled in Sri Lanka!

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    1. Sanath
      Thank you for the email with the news clip. The news presenter interviewed many who were quarantined at Diyatalawa under the auspices of the Military. To me Diyatalawa is a holiday resort but being under the care and supervision of the Military for a fortnight wouldn’t have made me jump for joy. All of them who were questioned heaped praise on the way the whole process was handled by the Military from start to finish. For the past 40 plus years all the information I heard about the Sri Lankan Armed Forces were less than complimentary. To hear such high praise from so many who were in quarantine about how well they were treated by everyone from the most junior soldier to high ranking officers and the medics makes me feel immensely proud to be Sri Lankan.
      It is more than 70 years since independence from colonial rule. English is not our mother tongue. Incidentally, the news presenter spoke perfect English with a superb Oxford accent. She indeed spoke better than some in the UK.
      These recent events have enhanced the reputation of my country. Let us not forget we were the jewel of the Indian ocean more highly rated than Singapore before it all fell apart in the 1960’s and 70’s. Perhaps we are now seeing the green shoots of progress and Sri Lanka will finally return to its former glory. May it happen in my lifetime.

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  32. Nihal, as I have mentioned to Zita many times I am always optimistic and tend to look towards the positive things in life. During the period of lockdown, there has been only one murder and only a single fatality due to a road traffic accident so far, in Sri Lanka. The government has banned the import of non-essential items so as to promote local production in the agriculture sector. A foreign economic advisor made the observation, few years ago that although ours is an island nation, some people are eating fish imported from Scotland! We have plenty of inland lakes and estuaries etc,and it is only in the recent years that fish(prawn)farming has progressed.I sincerely hope that after this global aftermath, we would become self-sufficient in food. I am proud to say that no one dies of starvation in our country, unlike in mother India and some African countries.

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    1. Dear Sanath and all,
      We must remember with gratitude,Mr D.S.Senanayake the “Father of the Nation”,whose primary goal was self sufficiency in food and upliftment of the rural masses.He also was a true Srilankan and abhorred division based on ethnicity,creed or language.A great man by any criterion.Like Abu Ben Adhem may his tribe increase.

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  33. Nihal, I really enjoyed reading your article in today's Sunday Island paper about your favourite singing duo, Nina and Frederick.

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    1. Thank you Sanath. The lockdown has some benefits too. It makes me sit down and write and recall some memories of long ago.

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  34. Sanath Lama and I both share our affinity for SL. Circumstances forced me to go to the US for a few years, mainly because of economic reasons. But like a magnet, my place of birth was beckoning me to come back, So here I am. Need I say that I am quite happy here.

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  35. Zita always brings up the tail end and I notice looking at the above comments that this article of Lucky's has been unique. Let me write the 56th (?) comment now and it would have done as one of the earliest comments as it does not refer to any of the above.

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  36. Sorry it got published before I had added the part below, and here it is!
    I really appreciate Lucky’s educative and informative article about the present state of the ‘pandemic’ of Coronavirus in Sri Lanka, with exact figures and facts about the epidemiology of this condition which is new to most of us. It throws light on the relative mildness of the pandemic of Covid-19 in Sri Lanka. We have been amazed at the efficiency of management and now we understand role of the military training of the heads of state must have been an advantage. This is in every way a fight against an unfamiliar enemy. There are lessons to be learned from every ‘war’ and this one has given the whole world many lessons in always being alert, not to be complacent and think ‘oh it is in that country or the other. It won’t involve us’ etc. Humans anywhere on the planet are susceptible to wars whether they be biological, financial or military and one has to be armed with all that is necessary. Zita

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  37. Thank you Lucky for this enlightening article. I did share it with my family, Nihal, thank you for your recollections of our beloved Dean. He was indeed wise, in the way that he handled the Castle Street incident. As some of you have commented it is quite commendable the way the crisis has been handled in Sri Lanka. I have only skimmed the the comments, and may get into more detail later. The situation in the US is chaotic, to say the least, because leadership is non-existent at a national level. Thank goodness for a few smart State Governors.

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  38. Kumar,I saw the father of the nation,Rt.Hon D S Senanayake,as a young boy,in my small town,when he attended a political meeting,in support of UNP candidate;Mr.D P Attygalle,younger brother of Sir Nicholas.He was very eloquent in colloquial Sinhalese and pleasing to the ears.I used to hear his voice,since his demise,when they played old records in SriLankan TV.It was a great loss to SriLanka,by his premature demise.His name will remain immortal,by the mere Senanayake ,Samudra.

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  39. Hi Nihal and Rohini

    Re: Your serious concerns about the CV mutations
    Last Sunday(19th April) I listened to Professor Sarah Gilbert a vaccinologist (leading the Oxford “Corona Virus Vaccine Trial”) being interviewed on the Andrew Marr show. Her response regarding Corona Virus mutations:

    “There are mutations going on but not at a level that will affect our ability to vaccinate against it. The differences among mutants of Corona viruses like SARS
    and MERS are quite minor unlike the Flu viruses where the differences among the mutants are great and change from year to year.”

    2. Re-infection possible
    Next question: possibility of reinfection following a corona virus infection.
    Her response: “Can’t say for certain with this particular CV, but from what we know of other CVs such as SARS and MARS that infect humans, the immunity is not long lived, so I think that it is likely that if someone gets infected they could get re-infected in the future. Unable to say after how long at this stage.



    3. Natural infection immunity weaker than vaccine induced immunity.
    There is a difference between immunity acquired after natural infection and immunity acquired after vaccination – they are not necessarily the same thing. The Professor added that the coronavirus is very good at not leaving behind a very good immune memory.
    Immune response to the vaccine
    A CV is not being used for the vaccine instead an Adeno virus is being used and a strong immune response that remains at a high level for a long time is expected. Therefore we could be in a situation in which the vaccine induced immunity could last a long time, ie longer than the infection induced immunity.

    5. Clinical Trial is starting tomorrow, 23 April when the first volunteer will be vaccinated. Initially the cohort will consist of healthy people between 18 and 55 years. Half the volunteers will get the Adeno virus vaccine and the other half will receive the placebo (meningitis) vaccine.

    On a lighter vein, a medical student was asked to describe a” double blind clinical trial” and the succinct reply was two orthopaedic surgeons trying to read an ECG.
    Apologies if you have heard this before.
    Bora

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  40. Bora
    Thank you for that lucid and comprehensive summary of the current knowledge on the topic. For the benefit of us all we hope the Oxford group have a successful trial.
    I do like the seamless entry into the 'fabulation'. Although I have heard it before just like the Covid-19 it didnt leave a lasting memory, hence I enjoyed it very much. We do need humour to survive the lockdown.

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  41. There is a hive of activity on the preparation of a vaccine. This is the only way we can beat the disease. The Imperial College group will start their trials in June using RNA of Sars-Cov2 virus. Meanwhile there will be trials to see the effectiveness of Ebola, HIV and Malaria treatments to treat Covid-19.
    Until they succeed we will remain at risk.
    They have government funding for their research and trials.

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    Replies
    1. Nihal
      I fully agree .people of our vintage are at risk.Even post lockdown I would be very reluctant to move freely in the community until a safe and effective vaccine is available or a therapeutic cure is found.I feel frustrated at what we are missing like social meetings,holidays etc.Then I tell myself what ever joy or satisfaction i would have got from these events would hav been for that moment only and then . goes into the memory bank.I should be grateful that I am in good health and be content with the situation I am in. i

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  42. Thanks,Bora,for making it lucid for reader who have lost their
    knowledge about the type of immunity obtained by individuals against various viral infections.We know the basic terms like acquired and passive immunities.Acquired immunities could last for few years or life long.Passive immunity does not last for ever with single vaccination.That is the reason why people need booster vaccinations.It is simple for medics like,us.

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    Replies
    1. Hi Sumathi
      Glad that you found it useful.I remember receiving Anti Tetanus Serum(ATS) ,passive immunisation,injections from Dr Shelton Karunaratne,whenever I cut myself with anything rusty or dirty.

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  43. What I like to know is how governments prepare for possible influenza pandemics. In the UK, there is a concerted effort to vaccinate vulnerable people. But we know that the HN virus mutates and the vaccine they make available is a cocktail including a best guess one for a mutated virus. What I am getting at is this. Is there an expert panel which does scenario planning and make sure that plans are there in case there is a pandemic. Covid was not expected but if scenario planning was done properly, the state of readiness of the NHS would have been far better. I heard that in the USA, there was such a Body and Donald Trump disbanded it. I don't know whether this is true or whether it is anti-Trump propaganda. In the NHS I am told, there was something called Operation Cygnus and I am trying to get some info on it. The report was called Emergency Preparedness Resilience and Response (EPRR) report.

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  44. This is part of a report in October 2017.
    NHS England prepared for and participated in Exercise Cygnus, a
    three-day exercise looking at the impact of a pandemic influenza
    outbreak, and the significant impacts on health delivery a widespread
    pandemic in the UK would trigger.

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  45. Hi Bora and Mahen, Thanks for tour update on the Oxford clinical trial study. Johns Hopkins did talk about this trial with optimistic expectation that the results will be available sometime in the summer. As to Mr. Trump yes a Pandemic committee of the national security council was created by President bush somewhere in the 2000, but since nothing had happened in near 2 decades President trump disbanded and was folded into the health and human services. Whether this committee would have identified Cov-19 earlier is anybody's guess.

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  46. Bora,
    Please pardon me for taking the liberty of addressing you as “Bora” in the manner of your long time buddies from school and med school, though I have not had the privilege of getting to know you in med school -
    Thank you for your very informative comment addressed to Nihal and myself on the 22nd which I just happened to see.
    It clarified and answered many issues that arose in my mind regarding immunity to Covid 19.
    The confidence of the Oxford university team in having a million doses of a vaccine ready by September if the clinical trials prove its efficacy is comforting as a start,
    with billions of doses required to control it globally.
    Have enjoyed the glimpses of Bora in the blog .
    Cheers
    Rohini

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  47. Hi Rohini
    No worries,feel free to call me Bora.Glad to hear that you found the info useful.I desperately hope that the Oxford group or any other group find a protective vaccine and liberate us from social distancing/isolation.
    Best wishes
    Bora

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    Replies
    1. Glad you are not hung up on how you are called Bora. I am called all sorts and I don't miod in the least- Speedy,Mahendra, Mahen, Gonsal, Gona, Gunsi, G-Kola GSK are just a few!

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    2. Mahen
      You are very tolerant but some medics are very sensitive if their names are spelled or pronounced incorrectly.A Scottish lady consulted me,In her Highland accent she gave me the name of her GP which I made out to be Dr Mackinlow and I thought that sounds very Scottish.
      I wrote to Dr M to obtain relevant information regarding her past history and investigations.I received a prompt reply which provided the information I requested and it ended as follows.".For your information I am not Scottish but a Sri Lankan.My name is Not Mackinlow. it is Makkulolu.....

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    3. Bora, that's so funny! Was it the famous Trinity rugby famed Makuloluwa married to Sriyani? You are right about sensitivity. Some Gompas don't like it at all.

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  48. Hi,Speedy,You reminded me of G-Kola,a drink that was made from dried Gotukola.There was a civil servant,who was head of the Ayurvedic Dept,got this product manufactured in SriLanka.In fact,I have tasted it myself.I am sure "Speedy" was the most popular name during the five years,in the Faculty.

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    Replies
    1. You are correct Sumathi. UVA De Silva coined the name. I was Gona or Gonsal at Royal. G-Kola and Gonzo was by some of my nurses at Ladywell and Hope (in my absence) but most called me Dr G in my presence. GSK was what the juniors put in request forms, Gunsi was by Jeff Babapulle, Mahendra was by family.

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